The alphamegalog of the cities of Indiana lists the largest city in Indiana for each letter of the alphabet. In this case, ‘largest’ is based on population within the city proper.

Anderson
Bloomington
Columbus
Dyer
Evansville
Fort Wayne
Gary
Hammond
Indianapolis
Jeffersonville
Kokomo
Lafayette
Muncie
Noblesville
Ossian
Portage
Quincy
Richmond
South Bend
Terra Haute
Upland
Valparaiso
Westfield
(no X)
Yorktown
Zionsville